IFNG and neoplasm: Of note, one species of Phascolarctobacterium has been positively correlated with induction of colonic interferon-γ (IFN-γ)-expressing CD8 T cells, and colonization of mice with a consortium of 11 bacterial strains, including Phascolarctobacterium faecium, has been shown to enhance both spontaneous and ICB-mediated anti-tumor activity by increasing CD8+ tumor infiltrating lymphocytes producing IFN-γ in syngeneic tumor models [37].