IGHE and neoplasm: Anti-MUC-1 IgE in an MUC-1-expressing 4T1 murine breast cancer model in combination with mast-cell-attracting chemokines led to tumor rejection, and importantly also led to the rejection of 4T1 cells subsequently on the contralateral flank in the absence of either the IgE antibody or chemokines, suggesting a memory immune response [87].