The aim of our study was to characterize the contractile response to Ang II in three regions of the colon—proximal colon (PC), middle colon (MC) and distal colon (DC)—of rats with 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced IBD [31] and to look for which cells and mediators participate in that effect of Ang II. Here, AGT is linked to inflammatory bowel disease.