Further possibilities for diagnosing specific oral and systemic diseases can also be obtained by saliva tests, such as the assessment of periodontal diseases and atherosclerosis by checking salivary inflammatory cytokines including IL-1β, IL-6, TNF-α and prostaglandin E2; acute myocardial infarction by evaluating the concentration of C reactive protein (CRP); and pancreatic cancer by searching for the presence of Neisseria elongate and Streptococcus mitis [25,26,27]. This evidence concerns the gene CRP and periodontal disorder.