GC and colorectal carcinoma: With the aim to apply vitamin D as a prognostic marker for CRC patients, a recent study by Yuan et al. also investigated the relationships between plasma vitamin D binding protein (VDBP), bioavailable or free 25(OH)vitamin D and CRC survival, concluding that prediagnostic circulating concentrations of VDBP were positively associated with survival, while neither bioavailable nor free 25(OH)vitamin D levels were associated with overall or CRC-specific mortality [163].