IGHE and allergic disease: It is possible that this variation could be attributed to the differences between the groups of participants: age (10 months [25] vs four months in our study), feeding method (currently breastfeeding 39% [25] vs 59% in our study), type of allergy (IgE-mediated [25] vs IgE + nonIgE-mediated (56 and our study)), type of allergenic food (egg [25] vs milk in our study) or, finally, genetic and environmental difference (China [56] vs Europe in our study).