BRCA1 and breast carcinoma: For pathologic profiles, the BRCA1+ group had a significantly increased likelihood of basal-like subtype breast cancer grade 2 (LR = 4.7, 95% CI: 3.0–7.2) or 3 (LR = 4.6, 95% CI: 3.9–5.5) or high-grade ovarian cancer (LR = 3.4, 95% CI: 2.6–7.5), while the BRCA2+ group had a significantly increased likelihood of luminal subtype breast cancer grades 2 (LR = 1.2, 95% CI: 1.02–1.4) and 3 (LR = 1.5, 95% CI: 1.1–1.9).