BRCA2 and ovarian cancer: The lifetime cumulative risk of ovarian cancer for BRCA2 carriers was 14.9% (95% CI: 7.4–28.5%): 15.8% (95% CI: 2.4–70.7%) in region 1, 8.6% (95% CI: 2.3–28.6%) in region 2, and 20.0% (95% CI: 7.5–46.4%) in region 3 (Figure 4c, Supplementary Table S14).