HAMP and obesity due to melanocortin 4 receptor deficiency: Overall, males displayed significantly higher median values of serum hepcidin (7.23 ng/mL ± 5.1) compared to females (5.74 ng/mL ± 4.6) (p < 0.001), with males classed as having obesity based on % BF displaying the highest values of serum hepcidin (Table 2).