Other stromal cell types capable of inducing EMT include cancer-associated fibroblasts employing paracrine TGF-β [78,79] or IL-32 and Integrin β3–p38 MAPK signaling [80], mesenchymal stromal cells producing lysyl oxidase [81], and endothelial cells via PAI-1 (SERPINE1) and CCL5 signaling [82]. The gene discussed is SERPINE1; the disease is cancer.