Another relation between SARS-CoV-2 and TKR activity in cancer might be established between the large number of proinflammatory cytokines and chemokines, which are largely responsible for acute respiratory distress syndrome and the tumor microenvironment, which has a strong impact on carcinogenesis; more explicitly, a link between the IL-6/JAK/STAT3 pathway and the plethora of proinflammatory molecules found in patients suffering from COVID-19. This evidence concerns the gene STAT3 and neoplasm.