Although we selected an upper BMI limit of ≤ 30 kg/m2 to avoid confounding effects of obesity on the fibroinflammatory profile in human follicular fluid, there were two cytokines, leptin (p = 0.0048) and IL-8 (p = 0.0173), that nevertheless were positively correlated with BMI in our sample population (Figure 3A). Here, LEP is linked to obesity due to melanocortin 4 receptor deficiency.