TGFB1 and obesity due to melanocortin 4 receptor deficiency: The observation that IL-8 and leptin levels correlated with BMI, but not age and that IL-3, IL-7, IL-15, TGFβ1, TGFβ3, and MIP-1 levels correlated with age, but not BMI suggest distinct fibroinflammatory responses in obesity and aging, and thereby unique mechanisms by which these factors negatively impact oocyte quality.