Moreover, TGFB2 expression was found to be higher in two BC cell lines transfected with HOXB7 (SKBR3, MDA-MB-231) and the knockdown of TGFB2 in MDA-MB-231 cells overexpressing HOXB7 seems to inhibit lung metastasis in mice. This evidence concerns the gene TGFB2 and breast cancer.