The BCG-CWS-adjuvanted (S+BCG-CWS) vaccination effectively attenuated the production of inflammatory cytokines including IL-6, TNF-α, and IFN-γ, in the lungs from all aged mouse groups (6 D, 2 W, 6 W, and 20 M) after lethal infection (Figure 6A–C). Here, IFNG is linked to infection.