CLOCK and metabolic syndrome: Several recent reports suggest that eating in synchrony with the circadian clock by shifting more energy and CH to the morning hours (i.e., high energy and CH breakfast), and reducing energy and CH consumption in the evening hours, facilitate weight loss, improve postprandial glycemia, and reduce appetite and craving in metabolic syndrome and in T2D, compared to the inverse pattern, i.e., “high in energy and CH dinner” and reduced breakfast [15,27,30,35,39,40,61,73,74,75,76,77].