Aiming to revisit MSI1′s connection to “hallmarks of cancer” gene sets, we investigated the association of MSI1 correlated genes to KEGG signaling pathways from the Kyoto Encyclopedia of Genes and Genomes in 19 TCGA RNA–Seq cohorts of solid cancers using the R2 platform (https://hgserver1.amc.nl/, accessed on 30 March 2021) (Figure 2D). Here, MSI1 is linked to cancer.