CCN1 and ovarian serous adenocarcinoma: Of note, extensive copy number alterations of MYC proto-oncogene BHLH transcription factor (MYC) have been observed in high-grade serous ovarian cancer [64], whereas BDNF appears to play a role in ovarian cancer, cell migration and angiogenesis [65] and cysteine-rich angiogenic inducer 61 (CYR61) is a potential biomarker for prognostic insinuations of ovarian carcinoma [66].