Besides PD and related synucleinopathies, it is also worth noting that the intraparenchymal delivery of rAAV-GBA1 in a transgenic mice model of Gaucher disease showed a reduction in misfolded protein aggregates of α-syn, tau and ubiquitin at the level of the hippocampal formation [17,18]. The gene discussed is MAPT; the disease is Gaucher disease.