The implication of a possible complex interplay between these immune cells via some targeted genes, such as IL10RB, IL13RA1 and IL22RA, predicted to be targeted by tsRNA-Glu-CTC-003 and upregulated in the mRNA sequencing data, and the BCL9 target of tsRNA-Glu-TTC-010, which was downregulated in the mRNA sequencing data (Figure 4 and Data Supplement V–VI), provides a basis for further exploration in MMD [23]. This evidence concerns the gene IL10RB and multiminicore myopathy.