In addition, 21 of 33 detected SNPs were located within nine chromosomal regions which were not previously associated with the same cancers at PGWAS < 5.0 × 10−6 (i.e., KHDRBS3/8q24.23 and GLRX3/10q26.3 (CRCa-F); PRKG1/10q21.1 (LCa-F); THRB/3p24.2, HTR1E/6q14.3, and MPHOSPH8/13q12.11 (CRCa-M); MAP7/6q23.3, ATP8B1/18q21.31, and GRIK1/21q21.3 (LCa-M)). Here, HTR1E is linked to cancer.