PD-L1 expression in DTCs, PDTCs and ATCs is associated with poor survival, especially in co-existence with BRAFV600E mutation [154,155], and is noted in 6.1% PTCs, 7.6% FTCs and 22.2% ATCs [156,157,158]. Here, CD274 is linked to Ehlers-Danlos syndrome, musculocontractural type.