The hearing loss in four other patients was caused by pathogenic biallelic variants in the well-known hearing loss-causing genes: STRC (OMIM 606440); MYO15A (OMIM 602666); SLC26A4 (OMIM 605646); and LOXHD1 (OMIM 613072). The gene discussed is LOXHD1; the disease is hearing loss disorder.