Because IFNs are required to stimulate the production of these chemokines by cDC1s, tumor-infiltrating T cells that secrete IFN-γ, namely cDC1-induced CTLs and cDC2-induced Th1 cells, establish a positive feedback loop that amplifies the cDC1-dependent recruitment of additional T cells [26]. Here, MPPE1 is linked to neoplasm.