Moreover, lipopolysaccharide (LPS)-activated 6-sulfo LacNAc+ (slan) DCs are able to activate NK cells by inducing CD69 expression, IFN-γ secretion, and tumor-directed cytotoxicity [81], thus confirming a regular circuit between human DCs and NK cells occurring in vivo, in which the resting NK cells require DCs for activation. Here, IFNG is linked to neoplasm.