Additionally, like CDKI-73, Wogonin and related flavones like Baicalein, Apigenin, Chrysin and Luteolin enhanced the activity of the specific BCL-2 inhibitor ABT-263 in primary AML and ALL cells and cell lines of different cancer entities, while also sensitizing cancer cells harboring acquired ABT-263 resistance [187,188]. This evidence concerns the gene BCL2 and acute lymphoblastic leukemia.