STAT3 and cardiomyopathy: In response to IL-27, gene expression of TBX21, EOMES, and CXCL9, which are activated downstream of STAT1, STAT3, and STAT5 phosphorylation, was lower in patients with cardiomyopathy (i.e., the G1 and G2 groups) than that in uninfected subjects (S4D–S4E and S4G Fig).