Patients with cardiomyopathy showed decreased expression of TBX21, EOMES, and CXCL9 (S4H–S4SI and S4K Fig) and unaltered GZMB (S4J Fig), while no difference was observed in T. cruzi-infected subjects without heart disease (S4H–S4K Fig) compared with uninfected subjects. Here, EOMES is linked to heart disorder.