CCR2 and COVID-19: Furthermore, a recent study that included whole-genome sequencing of 2244 patients with COVID-19 from 208 ICUs in the United Kingdom showed that critical and life-threatening COVID-19 has a genomic association with SNPs in mediators of organ inflammation genes, including those encoding tyrosine kinase 2, DPP9, and monocyte/macrophage chemotactic receptor CCR2 (71).