To this end, we found that SPOP depletion only moderately increased BRD4 proteins in MHH‐ES‐1 cells (Figure 1I) but not in other Ewing sarcoma cells (A673: Figure S1I (Supporting Information) and SN‐N‐MC: Figure S1J (Supporting Information)). This evidence concerns the gene SPOP and Ewing sarcoma.