C1QTNF9 and Right ventricular hypertrophy: In further studies, we overexpressed CTRP9 in HPH rats and demonstrated that CTRP9 could ameliorate alterations in pulmonary hemodynamics (as shown by RVSP), pulmonary vascular remodeling (as shown by MT% and MA%), right ventricular hypertrophy (as shown by RVHI) in HPH rats and aid survival.