In this study we have used genotypes of three SNPs in TERT, located on chromosome 5p15.33; rs2736108 (upstream variant) and rs7705526 (intronic variant) both of which have been associated with longer telomeres and breast cancer22, and rs2075786 (intronic variant) reported to be associated with shorter telomeres and increased cancer risk in LS29, using data from four different LS cohorts (two of the cohorts previously described for one of the SNPs in29). This evidence concerns the gene TERT and cancer.