SOCS5 and familial pancreatic carcinoma: Indeed, several miRs have been described to directly suppress SOCS5 expression in a variety of cancer cells, such as miR-9 in prostate cancer50, miR-885 in colorectal cancer51, miR-301a in pancreatic cancer cells33, or miR-18, miR-25, and miR-589 in liver cancer52,53.