STBD1 and lung carcinoma: Interestingly, overexpression of STBD1 WT, but not STBD1 W203C, significantly suppresses cell growth and colony formation in lung cancer cell line A549 cells (Fig. 4c–e, colony formation: plvx neo = 775 ± 30; STBD1 WT = 604 ± 16; STBD1 W203C = 699 ± 15).