STBD1 and neoplasm: Furthermore, shSTBD1/WT markedly suppresses tumor growth in the xenograft model, in comparison with control (plvx neo) and shSTBD1/W203C (Fig. 4o, p; the weight of tumor: plvx neo = 0.704 ± 0.181; STBD1 WT = 0.269 ± 0.145; STBD1 W203C = 0.515 ± 0.244).