To further investigate the quantitative correlation of MAPK14 and JAK2/STAT genes, global expression profile correlating with MAPK14 expression, uncovered that JAK (JAK2/JAK3) and STAT (STAT1/STAT3/STAT5A/STATA5B) family genes were positively correlated with MAPK14 in MPN patients (Fig. 7). The gene discussed is JAK2; the disease is myeloproliferative neoplasm.