A positive correlation was determined between serum DKK1 levels and serum sclerostin levels in the healthy control, SLE, and SS groups (respectively; r = 0.829, p < 0.001; r = 0.783, p < 0.001; and r = 0.677, p < 0.001). The gene discussed is SOST; the disease is systemic lupus erythematosus.