According to previous reports, increased gene expression and protein levels of hnRNP K and SET are frequent events in several types of cancer and they have been proposed to be prognostic markers in leukemia, mainly in CML, increasing during a blast crisis [5, 6, 22, 23, 35]. The gene discussed is HNRNPK; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.