1.RRT and AKI-1.1 Inflammatory Biomarkers:-AKI vs non-AKI: Ferritin (1016 vs. 680); D-dimer (1.57 vs. 1.13);CRP (163 vs. 93); Procalcitonin (0.37 vs. 0.12); LDH (532 vs. 428).-AKI-RRT: Higher baseline serum ferritin, CRP, procalcitonin, and LDH. Higher D-dimer median peak value (7.8 vs. 3.8, p=0.003).-1.2: Incidence:-Total cohort: 55.0%-ICU: 73.0%-1.3: Risk factors for RRT:-Younger age (61 vs. 68, p=0.0003);Higher BMI (35 vs. 33, p=0.05).-1.4 Mortality:-In-hospital mortality rate: 72.0%-AKI-RRT and MV: 74.0% This evidence concerns the gene CRP and acute kidney injury.