HK1 and Alzheimer disease: Among the oxidized proteins detected in the redox proteomics analysis to be reversed by MitoQ treatment in the patients, we found proteins implicated in glucose metabolism, like the beta subunit of the mitochondrial ATP synthase; and the gamma and alpha subunits of the glycolytic enzyme enolase—the latter has been consistently reported to be oxidatively modified in AD patients’ brains and animal models of the disease.58, 59, 60