ADAT3 and neurodevelopmental disorder: To evaluate the functional impact of the ADAT3-N domain in vivo and considering the implication of the p.Val128Met variant in neurodevelopmental disorders, we assessed the consequences of overexpressing mouse ADAT3 mutants together with ADAT2 in vivo in the mouse developing cortex using in utero electroporation (IUE) (Figure 8A).