We also analyzed the relationship between expression of FXR1 and clinical pathological parameters [tumor size, breast cancer biomarkers (ER, PgR and HER2), lymph node metastasis, ki67 and Nottingham grade], and found that the expression of FXR1 was positively correlated with lymph node metastasis (Supplementary Table 3). This evidence concerns the gene MKI67 and neoplasm.