In addition, reduced ratio of EdU-positive cells in TINCR-knockdown group was remarkably increased with TCPTP-siRNA co-transfection (Figure 2(g,h)), indicating that TINCR had an important role in regulating Hep3B and HCCLM3 HCC cells S phase of the cell cycle. This evidence concerns the gene PTPN2 and hepatocellular carcinoma.