These findings are notable both due to the very young age of the Krabbe disease patients in which α-synuclein pathology was observed, but also as variants in GALC are associated with increased risk of developing idiopathic Parkinson’s disease, this indicates a direct mechanistic link between Krabbe disease and age-associated Lewy body diseases (Kia et al. 2021; Li et al. 2018). The gene discussed is GALC; the disease is Krabbe disease.