Lewy body diseases are normally associated with advancing age, and incidental Lewy bodies are typically only observed in individuals over the age of 60 (Frigerio et al. 2011; Outeiro et al. 2019); therefore, the presence and severity of Lewy body pathology in individuals as young as 8 years old suggests an association between Lewy body pathology and PLA2G6 mutations. Here, PLA2G6 is linked to Lewy body dementia.