Median overall survival of adult diffuse hemispheric gliomas, H3 G34-mutant was 12.4 months compared to 19.6 months (P = .56), 11.7 months (P = .45), and 50.5 months (P = .006) in H3.3 K27M-mutant DMG, IDH-wildtype glioblastomas, and IDH-mutant glioblastomas, respectively (Figure 3). Here, IDH1 is linked to glioblastoma.