In addition, TERT promoter mutations were lacking in diffuse hemispheric gliomas in contrast to IDH-wildtype glioblastomas while MGMT promoter methylation was more frequent in diffuse hemispheric gliomas, H3 G34-mutant than in H3.3 K27M-mutant DMG and IDH-wildtype glioblastomas. The gene discussed is MGMT; the disease is glioblastoma.