IDH2 and neoplasm: The median overall survival of adult diffuse hemispheric gliomas, H3 G34-mutant herein is consistent with the median overall survival ranging from 12 to 36 months reported in previous series (Table 3).3,4,6,12,21,22,26 Although several studies suggested that diffuse hemispheric gliomas, H3 G34-mutant had a better prognosis than H3.3 K27M-mutant DMG4,10,30,31 the prognosis of these two tumor types was similar in the present series and was also similar to that of IDH-wildtype glioblastomas.