Within anaplastic astrocytomas, ATRX mutation is a favorable prognostic biomarker associating with longer survival outcome and ATRX wildtype has been found to associate with recurrence.32 To date, only one prior study has assessed radiomic prediction of ATRX status.14 They demonstrated predictability with AUC of 0.94 in LGGs using T2-weighted images. This evidence concerns the gene ATRX and anaplastic astrocytoma.