SREBF1 and hepatocellular carcinoma: SREBP1 is crucial for lipogenesis as well as HCC cell proliferation and metastasis [33]; in the current study, it was found that the expressions of these three proteins above were increased in HCC cells transfected by miR-603 mimic; the results indicated that miR-603 can promote the lipid accumulation and then accelerate the HCC progression.