However, in contrast to the case of rectal adenocarcinoma wherein high ALKBH5 expression in tumor tissues was clearly associated with worse OS, ALKBH5 expression in pancreatic cancer was found to be positively associated with OS in TCGA and ICGC, which was in accordance with the report by Cho et al. [31]. Here, ALKBH5 is linked to rectum adenocarcinoma.