Recently, a study has shown that ALKBH5 functions as an antitumor protein in pancreatic cancer progression [29]; in this paper, upregulated ALKBH5 sensitized pancreatic cancer to gemcitabine chemotherapy, and knockdown of ALKBH5 decreased pancreatic cancer cell invasion, migration, proliferation, metastasis, and tumorigenesis [29]. Here, ALKBH5 is linked to familial pancreatic carcinoma.