TNF and obstructive sleep apnea syndrome: In addition, vitamin D can inhibit the secretion of IL-2, TNF-α, and IFN-γ by Th-1 and promote the secretion of IL-4, IL-3, IL-5, and IL-10 by Th2, to inhibit the occurrence of chronic inflammation, which plays an important role in the occurrence and development of OSAHS.