Although there are studies describing lower numbers of neutrophils in eosinophilic CRSwNP compared to the non-eosinophilic polyps (Schleimer, 2017); other authors (Pothoven et al., 2017; Kong and Kim, 2018) have recently reported similar results, linking the role of neutrophils in this disease to their expression of oncostatin M (OSM), a cytokine that has been found elevated in CRSwNP and that induces barrier dysfunction. This evidence concerns the gene OSM and chronic rhinosinusitis with nasal polyps.