PROS1 and cancer: As summarized above, even though the exact mechanisms of how GRASP55, Golgin-160, GMAP210, and Golgin-97 regulates protein glycosylation are still missing in cancer cells, GM130, Giantin, and GOLPH3 were characterized to directly modulate specific localization of glycosylation enzymes in the right cisternae, indicating that Golgi structure or Golgi structural proteins probably functions in providing an ordered space for proper protein glycosylation.