The majority of subjects (11 out of 14) were azoospermic, and some of them presented with reduced testicular volumes, elevated luteinizing hormone (LH) levels, elevated follicle-stimulating hormone (FSH) levels and/or reduced serum testosterone (T) levels (Table 1), all signs of broad testicular dysfunction present in 60% of azoospermic men (Tüttelmann et al., 2018). This evidence concerns the gene BRD2 and testicular disorder.