PKD1 and cyst: Interestingly, LKB1 (STK11) was shown to be part of a ciliary module comprising NPHP1, NEK7, ANKS3 and polycystin-1 that regulates cilia-controlled secretion of CCL2, a chemokine that promotes macrophage recruitment and consequent cyst growth and interstitial inflammation (Viau et al., 2018).