reported that miR-15a/16 was up-regulated in serum of patients with neonatal sepsis; investigations into its mechanism revealed that lncRNA SHNG16 could act as a ceRNA and positively regulate TLR4 by competitively binding miR-15a/16 in LPS-induced macrophages, thus indicating that lncRNA SNHG16 affected inflammatory responses in neonatal sepsis (Wang et al., 2018). Here, TLR4 is linked to Neonatal sepsis.