For example, in our study mir-877-3p was found to bind to both of the circABCB1 and ABCB1 mRNA (Figure 4; Supplementary Table 8), which indicated that circABCB1 may act as a competing endogenous RNA (ceRNA) to sponge miR-877-3p and led to upregulation of ABCB1 expression and finally contribute to docetaxel resistance in breast cancer cell. This evidence concerns the gene ABCB1 and breast cancer.